I generate my presentations with org-mode in emacs and the beamer LaTeX class(pdf). I then display them as PDFs with the Preview app on my Mac, running in full screen mode. I use iRed Lite to enable controlling the presentation with my mac's included remote.

I also use Caffeine to prevent my laptop from going to sleep during the presentation.

Here's a nice guide on how to give a presentation by Glen Campbell.

This is the checklist I'm working on for everything I need to do prior to giving a presentation:

I just used this to give a talk at BayLISA on April 22, 2011. The slides from my talk can be found here on my website.

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